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  1. Review

    Sensorimotor circuitry involved in the higher brain control of coughing

    There is an overwhelming body of evidence to support the existence of higher brain circuitries involved in the sensory detection of airways irritation and the motor control of coughing. The concept that cough ...

    Stuart B Mazzone, Alice E McGovern, Seung-Kwon Yang, Ariel Woo, Simon Phipps, Ayaka Ando, Jennifer Leech and Michael J Farrell

    Cough 2013 9:7

    Published on: 6 March 2013

  2. Review

    Molecular signaling and targets from itch: lessons for cough

    Itch is described as an unpleasant sensation that elicits the desire to scratch, which results in the removal of the irritant from the skin. The cough reflex also results from irritation, with the purpose of r...

    Pamela Colleen LaVinka and Xingzhong Dong

    Cough 2013 9:8

    Published on: 6 March 2013

  3. Research

    Classification of chronic cough by systematic treatment cascade trial starting with beta agonist

    Chronic cough is one of the most challenging symptoms to diagnose and treat, not only because of the variety of underlying disorders but also its varying susceptibility to treatments. Etiological studies of ch...

    Hideyasu Shimizu, Masamichi Hayashi, Yuji Saito, Yuki Mieno, Yasuo Takeuchi, Fumihiko Sasaki, Hiroki Sakakibara, Kensei Naito and Mitsushi Okazawa

    Cough 2013 9:4

    Published on: 7 February 2013

  4. Research

    Modulation of cough response by sensory inputs from the nose - role of trigeminal TRPA1 versus TRPM8 channels

    Cough, the most important airways defensive mechanism is modulated by many afferent inputs either from respiratory tussigenic areas, but also by afferent drive from other organs. In animal models, modulation o...

    Tomas Buday, Mariana Brozmanova, Zuzana Biringerova, Silvia Gavliakova, Ivan Poliacek, Vladimir Calkovsky, Manjunath V Shetthalli and Jana Plevkova

    Cough 2012 8:11

    Published on: 3 December 2012

  5. Research

    Antitussive effects of the peripherally restricted GABAB receptor agonist lesogaberan in guinea pigs: comparison to baclofen and other GABABreceptor-selective agonists

    Gastroesophageal reflux disease (GERD) is a common cause of chronic cough. Both acid and nonacid reflux is thought to play a role in the initiation of coughing and cough hypersensitivity. The GABAB receptor agoni...

    Brendan J Canning, Nanako Mori and Anders Lehmann

    Cough 2012 8:7

    Published on: 1 October 2012

  6. Research

    PCR based bronchoscopic detection of common respiratory pathogens in chronic cough: a case control study

    Viral respiratory tract infection is the most frequent cause of acute cough and is reported at onset in about one third of patients with chronic cough. Persistent infection is therefore one possible explanatio...

    Peter W West, Angela Kelsall, Samantha Decalmer, Winifred Dove, Paul W Bishop, James P Stewart, Ashley A Woodcock and Jaclyn A Smith

    Cough 2012 8:5

    Published on: 14 September 2012

  7. Research

    Fundoplication in chronic intractable cough

    Airway reflux is a common cause of chronic cough and this is often refractory to medical therapy. Surgery in the form of Nissen fundoplication has been highly successful in the treatment of the classic reflux ...

    Shoaib Faruqi, Peter Sedman, Warren Jackson, Ian Molyneux and Alyn H Morice

    Cough 2012 8:3

    Published on: 19 July 2012

  8. Research

    The objective assessment of cough frequency: accuracy of the LR102 device

    The measurement of cough frequency is problematic and most often based on subjective assessment. The aim of the study was to assess the accuracy of the automatic identification of cough episodes by LR102, a co...

    Sophie Leconte, Giuseppe Liistro, Patrick Lebecque and Jean-Marie Degryse

    Cough 2011 7:11

    Published on: 1 December 2011

  9. Commentary

    Perspective on the human cough reflex

    This review dissects the complex human cough reflex and suggests hypotheses about the evolutionary basis for the reflex. A mechanosensory-induced cough reflex conveys through branches of myelinated Aδ nerve fi...

    Stuart M Brooks

    Cough 2011 7:10

    Published on: 10 November 2011

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