|
Anatomical Characteristics:
| | | |
|
Ganglionic Origin
|
Nodose
|
Jugular
|
Jugular
|
|
Extrapulmonary Termination
|
No
|
Yes
|
Yes
|
|
Intrapulmonary Termination
|
Yes
|
Yes
|
Few
|
|
Substance P Expression (%)
1
|
Yes (50)
|
Yes (90–100)
|
No (0)
|
|
TRPV1 Expression
2
|
Yes
|
Yes
|
Yes
|
|
Functional Characteristics:
| | | |
|
Conduction Velocity (m/sec)
|
<1
|
<1
|
~6
|
|
Mechanical Threshold
|
High
|
High
|
High
|
|
Sensitive to:
| | | |
|
Punctate Mechanical
|
Yes3
|
Yes3
|
Yes3
|
|
Capsaicin
|
Yes
|
Yes
|
Yes
|
|
Hypertonic Saline
|
Unknown
|
Yes
|
Yes
|
|
Bradykinin
|
Yes
|
Yes
|
Yes
|
|
Acid
|
Yes
|
Yes
|
Yes
|
|
Inflation (≤50 cmH
2
O)
|
No
|
No
|
No
|
|
Deflation/Collapse
|
No
|
No
|
No
|
|
Stretch
|
No
|
No
|
No
|
|
Bronchoconstriction
|
No
|
No
|
No
|
|
ATP
|
Yes
|
No
|
No
|
|
Serotonin (5-HT)
|
Yes
|
No
|
Unknown
|
|
Reflex Effects on Respiration
|
Apnea4
|
Apnea4
|
Apnea4
|
