Figure 4

Effect of BCTC on capsaicin-induced cough in non-sensitized guinea pigs. Figure demonstrates the cough suppressant activity of BCTC (0.01 – 3.0 mg/kg, i.p.) administered at 30 and 60 minutes before capsaicin (300 μM) provocation. Each bar represents the Mean ± SEM of the number of coughs produced by a 4 min exposure to capsaicin. Control animals were guinea pigs that received oral vehicle instead of BCTC and were exposed to capsaicin provocation. (*p < 0.05 compared to control animals using a Kruskal-Wallis in conjunction with a Mann-Whitney-U; n = 8–9 per treatment group).