Effect of capsazepine (A) and VDM11 (B) on high dose (3 mg/ml) anandamide-induced reduction of the number of coughs. Capsazepine was given by aerosol for 4 min before the inhalation of anandamide. The antitussive effect of VDM11 (10 mg/kg) was assessed 60 min after subcutaneous administration. Each column represents the mean with S.E. of 10 mice in each group. *P < 0.05 vs. vehicle (10% DMSO)-inhaled group. #P < 0.05 vs. respective pre-value.