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Table 3 Over-the-counter and prescription medicines available for the therapy of acute cough

From: Acute cough: a diagnostic and therapeutic challenge

Type of product

Component

Available in

combinations with

OTC or prescription; formulation

Cough suppressant

Benzonatate

-

Prescription; perles and capsules

 

DXM polistirex

-

OTC; extended-release suspension

 

DXM

Antihistamine: promethazine

Prescription; syrup

 

Hydrocodone

Agent to discourage overdose: homatropine

Prescription; tablet and syrup

 

Hydrocodone

Antihistamine: chlorpheniramine

Prescription; extended-release suspension and extended-release capsule

Antihistamine

Brompheniramine

-

Prescription; elixir and injection

 

Brompheniramine

Cough suppressant + decongestant:

DMX + pseudoephedrine

Prescription; syrup

 

Chlorpheniramine

Cough suppressant: codeine

Prescription; extended-release suspension

 

Clemastine

-

OTC or prescription; tablet and syrup

 

Desloratadine

-

Prescription; tablet and syrup

 

Desloratadine

Decongestant: pseudoephedrine

Prescription; extended-release tablet

 

Dexbrompheniramine

Decongestant: pseudoephedrine

OTC; extended-release tablet

 

Dexbrompheniramine

Decongestant + antipyretic: pseudoephedrine + acetaminophen

OTC; extended-release tablet

 

Diphenhydramine

-

Prescription; injection, elixir and capsule

 

Loratadine

-

OTC; tablet and syrup

 

Loratadine

Decongestant: pseudoephedrine

OTC; extended-release tablet

 

Promethazine

Cough suppressant: codeine

Prescription; syrup

 

Promethazine

Cough suppressant + decongestant:

codeine + phenylephrine

Prescription; syrup

 

Promethazine

Cough suppressant + decongestant + antihistamine: codeine + phenylephrine + triprolidine

Prescription; syrup

Expectorant

Guaifenesin

-

OTC; tablet

 

Guaifenesin

Cough suppressant: DXM

OTC; tablet

 

Guaifenesin

Decongestant: pseudoephedrine

OTC; tablet

  1. OTC = over-the-counter; DXM = dextromethorphan