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Table 1 Patients' characteristics

From: Features of cough variant asthma and classic asthma during methacholine-induced brochoconstriction: a cross-sectional study

  Classic asthma Cough variant asthma p-value
  n = 58 n = 55  
Age (yr) 44.4 ± 15.9 43.2 ± 16.5 0.71
Male/Female (No) 29/29 33/22 0.29
Disease duration at diagnosis (yr) 6.7 ± 10.0 2.8 ± 4.4 0.10
Current smoking (Yes, %) 19.0 5.2 0.029
Atopic status* (Yes, %) 71.4 67.9 0.69
Blood eosinophils (number/μl) 389 ± 247 310 ± 404 0.011
FEV1 (% predicted) 86.8 ± 19.2 92.1 ± 17.6 0.14
FEV1/FVC (%) 72.6 ± 11.3 81.8 ± 8.9 < 0.0001
Baseline Rrs (cm H2O/L/sec) 4.3 ± 2.0 4.0 ± 3.2 0.040
Log Dmin (units) -0.20 ± 0.82 0.36 ± 0.60 < 0.0001
SRrs (cm H2O/L/sec/min) 2.9 ± 3.2 2.1 ± 2.1 0.042
Log C5 (μM) 1.51 ± 0.79 (n = 18) 1.17 ± 0.71 (n = 22) 0.15
  1. Values are given as the means ± SD.
  2. *: measured in 56 patients with classic asthma and 53 patients with cough variant asthma. Patients were considered atopic when 1 or more specific IgE antibodies were positive for cat dander, dog dander, weed, grass pollen, mold, or house dust mite.
  3. Abbreviation: Rrs, respiratory resistance. Dmin, cumulative dose of inhaled methacholine at the inflection point, where which respiratory resistance begins to increase. SRrs, slope of the methacholine dose-response curve for Rrs. C5, cough threshold, the lowest concentration of capsaicin that induces 5 or more cough.