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Table 2 Airway responsiveness to methacholine, DI index and number of coughs for 32 min during and following the inhalationof methacholine

From: Bronchodilator effect of deep inspiration and bronchoconstriction-triggered cough

Airway responsiveness

 

   PC20-FEV1

71.6 (GSEM, 1.28) mg/ml

   PC35-MEF40

21.1 (GSEM, 1.28) mg/ml

   PC35-PEF40

6.22 (GSEM, 1.27) mg/ml

After inhalation of PC20-FEV1 concentration of methacholine

 

   Percent decrease in FEV1 from the baseline value

22.0 ± 9.0%

   Percent decrease in MEF40 from the baseline value

53.4 ± 20.8%

   Percent decrease in PEF40 from the baseline value

63.0 ± 18.2%

   (MEF40-PEF40)/PEF40 ratio (DI index)

0.41 ± 0.39

   Number of coughs

39.3 ± 29.7/32 min