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Table 2 Investigative workup for etiology of chronic cough and sleep-apnea specific workup in patients with chronic cough

From: Chronic cough and obstructive sleep apnea in a community-based pulmonary practice

INVESTIGATIONS PERFORMED

N (%)

Pulmonary Function Tests

 

Spirometry

70/75 (93%)

Diffusion capacity

60/75 (80%)

Lung volumes

44/75 (59%)

Methacholine challenge testing

2/75 (3%)

Six-minute walk test

1/75 (1%)

Radiologic studies

 

Chest X-ray

54/75 (72%)

Chest CT scan

10/75 (13%)

Sinus imaging

10/75 (13%)

Endoscopic studies

 

Bronchoscopy

0/75

Upper GI endoscopy

2/75 (3%)

24 hour pH monitoring

1/75 (1%)

(Bravo* pH probe)

 

Laboratory studies

5/75 (7%)

SLEEP APNEA RELATED WORKUP

 

Sleep history obtained

41/75 (55%)

Abnormal

36/75 (48%)

Screening overnight oximetry

6/75 (8%)

Abnormal

6/75 (8%)

Polysomnography

38/75 (51%)

   Sleep disordered breathing

33/75 (44%)

No OSA (AHI < 5)

4/75 (5%)

Mild OSA (AHI 6-15)

6/75 (8%)

Moderate OSA (AHI 16-30)

6/75 (8%)

Severe OSA (AHI >31)

14/75 (19%)

   Periodic limb movement disorder

1/75 (1%)

   Sleep efficiency (mean)

89%

   Arousal index (mean)

17

   Oxygen saturation (mean)

91%

   Lowest oxygen saturation (mean)

78%

  1. Abbreviations: OSA - Obstructive sleep apnea; AHI - Apnea hypopnea index.
  2. * Bravo pH capsule with delivery system (Medtronic, Inc. Minneapolis, MN, USA)