Table 1 IOS indices Pre and Post Citric acid Cough challenge (n = 39).
From: Validation of the ERS standard citric acid cough challenge in healthy adult volunteers
IOS Variable | CA cough challenge with KoKo DigiDoser | CA Challenge with Mefar dosimeter | P value |
|---|---|---|---|
Baseline | |||
R5 (kPa/L/sec) | 0.331 (0.30,0.36) | 0.334(0.30,0.37) | 0.95 |
R20 (kPa/L/sec) | 0.281(0.26,0.31) | 0.282 (0.25,0.31) | 0.99 |
R5-R20 (kPa/L/sec) | 0.050 (0.04,0.60) | 0.052 (0.40,0.64) | 0.89 |
X | -0.09 (-0.96,-0.8) | -0.09 (-0.10,-0.08) | 0.77 |
Response to citric acid | |||
ΔR5(%) | -2.13(-5.52,1.25) | -2.51(-7.72,2.70) | 0.75 |
ΔR20(%) | -2.27(-5.48,0.94) | -0.12(-4.30,4.08) | 0.53 |
ΔR5-R20(%) | -5.78(-21.7,10.17) | -34.08(-68.8,0.67) | 0.17 |
ΔX(%) | 3.51(-0.64,7.65) | -6.89(-15.21,1.42) | 0.03* |