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Table 4 Within day and between day repeatability of Mean log C2 measurements from baseline measured at 1,2,4 hrs and 2 wks following citric acid inhalation challenge with the KoKo DigiDoser versus the Mefar Dosimeter.

From: Validation of the ERS standard citric acid cough challenge in healthy adult volunteers

Method

Within day (n = 39) base 1,2,4 hrs

Between day (n = 39) baseline, 2 wks

 

ICC (95%CI)

SEM

CV(%)

LOA

ICC (95%CI)

SEM

CV(%)

LOA

KoKo Digidoser

0.68(0.55-0.80

0.04

-2.2

-3.38, 3.01

0.70(0.55-0.86)

0.05

4.2

-3.34, 4.46

Mefar Dosimeter

0.67(0.54-0.80)

0.05

-14.8

-5.89, 2.57

0.41(0.14-0.67)

0.06

-10.7

-7.80, 4.36

  1. ICC: intraclass correlation, CI: confidence interval, LOA: limits of agreement, CV: coefficient of variation.