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Table 4 Within day and between day repeatability of Mean log C2 measurements from baseline measured at 1,2,4 hrs and 2 wks following citric acid inhalation challenge with the KoKo DigiDoser versus the Mefar Dosimeter.

From: Validation of the ERS standard citric acid cough challenge in healthy adult volunteers

Method Within day (n = 39) base 1,2,4 hrs Between day (n = 39) baseline, 2 wks
  ICC (95%CI) SEM CV(%) LOA ICC (95%CI) SEM CV(%) LOA
KoKo Digidoser 0.68(0.55-0.80 0.04 -2.2 -3.38, 3.01 0.70(0.55-0.86) 0.05 4.2 -3.34, 4.46
Mefar Dosimeter 0.67(0.54-0.80) 0.05 -14.8 -5.89, 2.57 0.41(0.14-0.67) 0.06 -10.7 -7.80, 4.36
  1. ICC: intraclass correlation, CI: confidence interval, LOA: limits of agreement, CV: coefficient of variation.