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Table 1 Bronchoalveolar lavage cell analysis

From: Involvement of nitric oxide (NO) in cough reflex sensitivity between non-sensitized and OVA-sensitized guinea pigs

Total cells (105 cells/mL) Mac (%) Neu (%) Lym (%) Eos (%)
non-sensitized guinea pigs
   Control 1.11 ± 0.11 71.8 ± 7.1 9.2 ± 5.6 1.8 ± 0.8 16.8 ± 5.6
   ONO1714: 0.1 mg/kg 1.09 ± 0.12 74.5 ± 4.3 6.2 ± 1.5 1.4 ± 0.4 17.9 ± 4.7
   ONO1714: 0.3 mg/kg 0.88 ± 0.09 76.0 ± 2.1 5.3 ± 3.3 1.5 ± 0.5 17.7 ± 1.6
OVA sensitized guinea pigs
   Control 2.63 ± 0.26 24.1 ± 3.1 2.5 ± 0.6 0.9 ± 0.3 72.4 ± 3.1
   ONO1714: 0.1 mg/kg 2.68 ± 0.12 25.1 ± 1.0 2.8 ± 0.3 0.5 ± 0.2 71.6 ± 1.4
   ONO1714: 0.3 mg/kg 2.64 ± 0.36 28.5 ± 3.6 0.8 ± 0.3 0.8 ± 0.3 69.9 ± 3.7
  1. BAL was performed immediately after cough reflex sensitivity in non-sensitized guinea pigs. Whereas in OVA sensitized guinea pigs, BAL was performed 24 h after cough reflex sensitivity. MAC, macrophages; NEU, neutrophils; LYM, lymphocytes; EOS, eosinophils