Review: Effect of drugs on human cough reflex sensitivity to inhaled capsaicin

Cough

Table 2 Drugs shown not to inhibit cough reflex sensitivity to capsaicin

1^stauthor	Ref. #	Year	Drug	Subject population
Ryan M	[38]	2012	gabapentin	chronic cough
Yousaf N	[39]	2010	erythromycin	chronic cough
Dicpinigaitis P	[10]	2009	benzonatate	viral URI
Dicpinigaitis P	[12]	2008	tiotropium	healthy volunteers
Davenport P	[40]	2007	codeine	healthy volunteers
Dicpinigaitis P	[41]	2003	fexofenadine	healthy volunteers
Dicpinigaitis P	[17]	2003	guaifenesin	healthy volunteers
Ishiura Y	[18]	2003	ambroxol	asthma
Ishiura Y	[19]	2003	pranlukast	chronic bronchitis
Dicpinigaitis P	[42]	2001	celecoxib	asthma
Fujimura M	[43]	2000	mexiletine	healthy volunteers
Dicpinigaitis P	[44]	1999	zafirlukast	asthma without cough
Capon D	[45]	1996	dextromethorphan	healthy volunteers
Hansson L	[46]	1994	nicotine	healthy nonsmokers
Hutchings H	[47]	1994	codeine	healthy volunteers
O’Connell F	[48]	1994	clonidine	healthy volunteers
Fujimura M	[49]	1993	procaterol	asthma, chronic bronchitis
Choudry N	[50]	1993	MAO inhibitors	healthy volunteers
Stone R	[51]	1993	5-HT (serotonin)	healthy volunteers
Fujimura M	[52]	1992	procaterol	healthy volunteers
Ventresca P	[53]	1992	furosemide	healthy volunteers
Karlsson J	[54]	1992	furosemide, HCTZ	healthy volunteers
Studham J	[55]	1992	terfenadine	healthy volunteers
Choudry N	[56]	1991	inhaled mu opioid agonist	healthy volunteers
Smith C	[57]	1991	salbutamol, ipratropium	healthy volunteers
Choudry N	[58]	1991	granisteron (5-HT3)	healthy volunteers
McEwan J	[35]	1990	sulindac	idiopathic cough
Hansson L	[59]	1988	nedocromil	healthy volunteers
Fuller R	[37]	1988	inhaled opiates	healthy volunteers
Collier J	[4]	1984	sodium cromoglycate	healthy volunteers

Abbreviations: URI-acute upper respiratory tract infection; MAO-monoamine oxidase; HCTZ-hydrochlorothiazide.