Cough

Table 2 Values of cough reflex sensitivity obtained in TRPA1 line of the study

From: Modulation of cough response by sensory inputs from the nose - role of trigeminal TRPA1 versus TRPM8 channels

	Saline	Vehicle	Isocyanate	Cinnamaldehyde
C2
Cu	10.1	13.8	6.8 *	12.1
C2 GM	12.5	16.8	10.8	12.6
GSD	3.2	2.6	4.3	6.7
CI min	8.3	10.6	6.8	7.5
CI max	15.7	17.2	12.8	13.7
C5
GM	198.4	183.7	277.4	287.1
GSD	4.4	4.8	4.3	3.46
CI min	196.4	181.6	148.4	166.5
CI max	200.4	185.8	518.4	495.36

Note: data are expressed in μM, GM – geometric mean, GSD – geometric standard deviation, CI min, CI max – 95% confidence intervals with alpha = 0.05. *p<0.05, Cu – urge to cough, C2 – concentration of capsaicin inducing 2 or more coughs, C5 - concentration of capsaicin inducing 5 or more coughs.

Back to article page