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Table 2 Values of cough reflex sensitivity obtained in TRPA1 line of the study

From: Modulation of cough response by sensory inputs from the nose - role of trigeminal TRPA1 versus TRPM8 channels

  Saline Vehicle Isocyanate Cinnamaldehyde
C2
Cu 10.1 13.8 6.8 * 12.1
C2 GM 12.5 16.8 10.8 12.6
GSD 3.2 2.6 4.3 6.7
CI min 8.3 10.6 6.8 7.5
CI max 15.7 17.2 12.8 13.7
C5
GM 198.4 183.7 277.4 287.1
GSD 4.4 4.8 4.3 3.46
CI min 196.4 181.6 148.4 166.5
CI max 200.4 185.8 518.4 495.36
  1. Note: data are expressed in μM, GM – geometric mean, GSD – geometric standard deviation, CI min, CI max – 95% confidence intervals with alpha = 0.05. *p<0.05, Cu – urge to cough, C2 – concentration of capsaicin inducing 2 or more coughs, C5 - concentration of capsaicin inducing 5 or more coughs.