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Table 3 Values of cough reflex sensitivity obtained in TRPM8 line of the study

From: Modulation of cough response by sensory inputs from the nose - role of trigeminal TRPA1 versus TRPM8 channels

  Saline Vehicle (+) Menthol (−) Menthol
C2
Cu 11.8 12.7 26.5 * 22.4*
C2 GM 12.5 14.7 31.3 * 26.3*
GSD 4.6 2.7 5.9 6.1
CI min 10.4 11.3 28.9 23.8
CI max 14.7 17.2 33.6 28.7
C5
GM 261 249 458.5 478.8
GSD 4 4.3 3.1 2.9
CI min 259 248 456.8 477
CI max 263 251 460.2 480.5
  1. Note: data are expressed in μM, GM – geometric mean, GSD – geometric standard deviation, CI min, CI max – 95% confidence intervals with alpha = 0.05. *p<0.05, Cu – urge to cough, C2 – concentration of capsaicin inducing 2 or more coughs, C5 concentration of capsaicin inducing 5 or more coughs.