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Table 1 Clinical characteristics of the patients

From: Successful resolution of refractory chronic cough induced by gastroesophageal reflux with treatment of baclofen

  Patient 1 Patient 2 Patient 3
Ages (yr) 26 63 42
Gender (M/F) M F M
Cough duration (month) 42 24 25
Heartburn Yes Yes No
Regurgitation Yes Yes Yes
Cough symptom score
 Daytime 3 4 3
 Nighttime 1 2 2
Cough threshold to capsaicin
 C2(μmol/L) 0.49 0.49 1.95
 C5(μmol/L) 31.2 1.95 7.8
FEV1 (%predicted) 99.1 101.8 86.1
FVC (%predicted) 96.9 104.0 96.1
FEV1/FVC (%) 89.5 83.8 75.0
PD20FEV1(μmol) >7.8 >7.8 >7.8
  1. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PD20FEV1: the cumulative provocative dose of histamine causing a 20% fall in FEV1.