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Table 1 Clinical characteristics of the patients

From: Successful resolution of refractory chronic cough induced by gastroesophageal reflux with treatment of baclofen

 

Patient 1

Patient 2

Patient 3

Ages (yr)

26

63

42

Gender (M/F)

M

F

M

Cough duration (month)

42

24

25

Heartburn

Yes

Yes

No

Regurgitation

Yes

Yes

Yes

Cough symptom score

 Daytime

3

4

3

 Nighttime

1

2

2

Cough threshold to capsaicin

 C2(μmol/L)

0.49

0.49

1.95

 C5(μmol/L)

31.2

1.95

7.8

FEV1 (%predicted)

99.1

101.8

86.1

FVC (%predicted)

96.9

104.0

96.1

FEV1/FVC (%)

89.5

83.8

75.0

PD20FEV1(μmol)

>7.8

>7.8

>7.8

  1. FEV1: forced expiratory volume in one second; FVC: forced vital capacity; PD20FEV1: the cumulative provocative dose of histamine causing a 20% fall in FEV1.