Table 1 Characteristics of the 10 patients with CIC
From: Clinical experience with low-dose itraconazole in chronic idiopathic cough
Case | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 |
|---|---|---|---|---|---|---|---|---|---|---|
Age (yr) | 63 | 70 | 68 | 69 | 67 | 55 | 62 | 71 | 47 | 63 |
Gender | M | F | M | F | F | M | F | F | F | F |
Smoking | ex-smoker | never | never | never | never | never | never | never | never | never |
Duration (Month) | 49 | 68 | 66 | 70 | 44 | 64 | 48 | 27 | 41 | 62 |
WBC | 4350 | 5800 | 8100 | 5600 | 5900 | 6600 | 4000 | 4900 | 3000 | 5400 |
Eo (%) | 2.4 | 5.2 | 1.1 | 1.7 | 1.1 | 0 | 1.4 | 1 | 3.2 | 1.7 |
IgE (IU/ml) | 179 | 20 | 97 | 119 | 734 | 75.5 | 16 | 38 | 20 | 29 |
FVC | 2.78(81.0) | 2.64(118.9) | 4.67(137.0) | 2.46(108.4) | 3.46(149.8) | 3.70(98.9) | 2.94(126.2) | 2.69(123.4) | 2.95(110.5) | 2.17(87.1) |
FEV1 | 2.13(80.1) | 1.90(118.7) | 3.62(138.2) | 1.93(114.9) | 2.69(152.0) | 3.07(96.5) | 2.56(143.0) | 2.20(144.7) | 2.53(106.3) | 1.67(80.7) |
FEV1/FVC (%) | 76.6 | 72 | 77.5 | 78.5 | 77.7 | 83 | 87.1 | 81.8 | 85.8 | 77 |
Reversibility (%) | 1.2 | 2.6 | −3.6 | 5.7 | 3.7 | 1.3 | 0.4 | 0.9 | 5.9 | 2.4 |
Rt-Meth (mg/mL) | 20000< | 20000< | 20000< | 20000< | 20000< | 20000< | 5000 | 20000< | 20000< | 20000< |
Cough (μM) | 0.98 | 31.3 | 62.5 | 31.3 | 1.95 | 15.6 | 3.91 | 0.49 | 0.49 | 1.95 |