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Table 2 The responses to the budesonide treatment in 39 chronic cough patients divided by the baseline saline and histamine test results

From: Capability of hypertonic saline cough provocation test to predict the response to inhaled corticosteroids in chronic cough: a prospective, open-label study

  Baseline saline test Baseline histamine challengea
Negative p Positive Negative p Positive
  (N = 19)   (N = 20) (N = 19)   (N = 19)
Response magnitude (points) 4.45 (2.95 – 5.94) 0.50 3.61 (2.37 – 4.85) 2.78 (1.55 – 4.01) 0.006 5.08 (3.76 – 6.40)
Response speedb (weeks) 1.34 (0.60 – 2.98) 0.72 1.46 (0.68 – 3.15) 2.70 (1.23 – 5.93) 0.008 0.72 (0.36 – 1.43)
  1. Response magnitude was defined as the maximal improvement in LCQ total score at any time point of the study. Response speed was defined as the time in weeks from the start of budesonide treatment to the appearance of minimal important change in LCQ total score.
  2. aHistamine challenge was missed in one subject due to technical reasons.
  3. bGeometric means and 95% confidence intervals.