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Table 3 Associations of the baseline test results with the magnitude and the speed of the budesonide response (N = 39)

From: Capability of hypertonic saline cough provocation test to predict the response to inhaled corticosteroids in chronic cough: a prospective, open-label study

  Magnitude of the response Speed of the response
Saline CDR Rs = -0.09, p = 0.59 Rs = 0.12, p = 0.45
Nitric oxide level Rs = 0.37, p = 0.020 Rs = -0.31, p = 0.055
Histamine RDRa Rs = 0.47, p = 0.003 Rs = -0.49, p = 0.002
FEV1 Rs = -0.16, p = 0.32 Rs = 0.23, p = 0.17
FEV1 rise after salbutamol Rs = 0.10, p = 0.55 Rs = -0.12, p = 0.48
Mean PEF variation Rs = 0.18, p = 0.28 Rs = -0.21, p = 0.19
  1. a Histamine challenge was missed in one subject due to technical reasons.
  2. Rs Spearman correlation coefficient.
  3. Magnitude of the response was defined as the maximal improvement in LCQ total score at any stage of the treatment. Speed of the response was defined as the time in weeks from the start of budesonide treatment to the appearance of minimal important change in LCQ total score.