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Table 1 Adjusted mean scores from daily diary card recordings of cough (0–3 intensity scale) from the TRISTAN study (24)

From: Cough in chronic obstructive pulmonary disease: is it important and what are the effects of treatment?

  Adjusted mean Treatment effect (SFC-comparator) 95% CL p-value
Placebo     
(n = 357) 1.44 −0.091 −0.17, -0.02 0.018
Salmeterol     
(n = 370) 1.36 −0.018 −0.09, 0.06 0.639
FP     
(n = 368) 1.38 −0.037 −0.11, 0.04 0.340
SFC     
(n = 351) 1.35 - - -
  1. Note that not all patients report cough and the scale not being validated for its measurement properties. Despite this the combination of bronchodilator and inhaled corticosteroid was associated with significantly less cough during the one year study period.
  2. FP Fluticasone propionate.
  3. SFC Salmeterol Fluticasone propionate Combination.